Existing approved uses of platform data

Research proposals

Please review these proposals before submitting a data access request. In the interest of maximising the production of evidence to reduce the impact of COVID-19, the platform aims to avoid unnecessary duplication of analyses.

ISARIC Partner Analyses

These analyses are submitted by researchers who contribute data to the ISARIC clinical data platform, and were approved by the ISARIC governance committee.

Read ISARIC Data Platform Publication Policy for more information on the publication of analyses.

Automatic Identification of Signals in Clinical Notes using Natural Language
Processing

University of Oxford, UK

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The relative influence of clinical and sociodemographic variables on the long-term COVID-19-associated QALYs lost

Harvard University, USA and University of Oxford, UK

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Predicting Long-COVID Syndrome Machine Learning Models (PRELOCS)

Institute for Clinical Research, National Institutes of Health Malaysia

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Cardiovascular comorbidities and complications in hospitalized patients with COVID-19

University of Oxford, UK and Serdang Hospital, Malaysia

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Statistical and machine learning methods for predicting risk of pulmonary embolism and death in patients with COVID-19

University of Oxford, UK and Queen Elizabeth Hospital, UK and Digital Health Research and Innovation Unit, Malaysia

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Comparing clinical presentation and outcomes of hospitalised SARS-CoV-2 patients before and after the spread of the Omicron variant

National Institute of Communicable Diseases, South Africa and King Abdulaziz Medical City, Saudi Arabia and Sunnybrook Health Sciences Centre, Canada and University College Dublin, Ireland and Franciscus Gasthuis & Vlietland, Netherlands and University of Oxford, UK and University Hospital of Tubingen, Germany

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Characterising SARS-CoV-2 Omicron vs Delta variant in terms of vaccination status, clinical presentation and outcomes

National Institute of Communicable Diseases, South Africa and King Abdulaziz Medical City, Saudi Arabia and Sunnybrook Health Sciences Centre, Canada and University College Dublin, Ireland and Franciscus Gasthuis & Vlietland, Netherlands and University of Oxford, UK

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Characterization of long term Covid-19 outcomes in different populations: ISARIC Global Collaborative Adult Covid-19 Follow up analysis

University of Glasgow Center for Virus Research, UK and Universidad de la Sabana, Chía, Colombia and Sechenov University, Russia and University of Oxford, UK

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A tool-box for epidemic research: the ISARIC Clinical Characterisation group on strategies to simplify and improve collaboration-fuelled research during health emergencies

University of Oxford, UK and Apollo Hospitals, Chennai, India and National Public Health Institute, Liberia

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Impact of COVID-19 in Pregnancy

 Mount Kenya University, Thika, Kenya and University of Oxford, UK

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Monitoring of COVID-19-associated outcomes across countries and over time in relation to the publication of therapeutic guidelines

Université de Sherbrooke, Canada

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Variation in management and outcomes of hospitalized patients with COVID-19 among low-, middle- and high-income countries

College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, and Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia

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Characteristics, presentation, risk factors, treatments and outcomes in patients with cancer and COVID-19 (ARC: ISARC International Cancer)

University of Oxford, UK and University of Liverpool, UK

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Prevalence of use and outcomes of Non-invasive oxygenation strategies as firstline treatment of COVID-19 respiratory failure

Fondazione Policlinico Universitario A. Gemelli IRCCS, Italy

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Liver function abnormalities in patients admitted with COVID-19 and association with outcomes: A draft analysis plan using data collected by the ISARIC Collaborators

Department of Hepatology, Apollo Hospitals, Chennai, India

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Lymphopenia in severe COVID19 patients: are they a unique immunologically compromised population?

Hospital São Francisco Xavier, Lisbon, Portugal

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Cardiovascular impact in COVID19 patients: a multicenter cohort analysis

Hospital São Francisco Xavier, Lisbon, Portugal

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Extracorporeal Membrane Oxygenation for COVID-19 Respiratory Distress Syndrome: a ISARIC Risk Factor Analysis

ALMA Mater Studiorum University of Bologna, Division of Cardiac Surgery, MCS Program, IRCCS Bologna; Bologna, Italy

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Clinical outcomes in children with severe covid-19: a retrospective study in limited vs. enormous resource countries

Pediatric Cardiac ICU National Cardiovascular Center Harapan Kita, Jakarta, Indonesia

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COVID-19 Among Healthcare Workers in a Worldwide Multi-center Study: Geographical Distribution, Characteristics and Outcomes

CUB-Hopital Erasme, Belgium and National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa

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Applicability of commonly used COVID-19 clinical case definitions and severity score amongst patients hospitalized with COVID-19 in low-and middle-income countries

University of Oxford, UK and Oxford University Clinical Research Unit-Nepal, Nepal

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Risk to admission of COVID19 patients from the Emergency Department

Hospital Universitario La Paz, Madrid, Spain and Universidad del Cauca, Cauca, Colombia

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Potassium in COVID-19 patients admitted to the hospital

Université de Lorraine, France and Hospital Civil de Guadalajara, Mexico

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Influence of nutrition status on COVID-related outcome

CUB-Hopital Erasme, Belgium

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Analysis Plan for ISARIC International COVID-19
Cohort

University of Oxford, UK

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Utility of measures of oxygenation for COVID-19 case management and outcome

University of Oxford, UK and Apollo hospitals group, India

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Coagulopathy and thrombosis among COVID-19 patients: Variation by geographical
location and healthcare setting

University of Utah/ University of Utah School of Medicine, USA

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Development of predictive analytics model for need of extracorporeal support in COVID-19

INOVA Fairfax Hospital and Washington University in St Louis, US

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Acute Kidney Injury in COVID-19

Faculty of Medicine, The University of Queensland, Australia and School of Mathematics and Physics, University of Queensland, Australia

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Neurological manifestation and outcome for patients admitted to hospital with
COVID-19: Results from the ISARIC prospective multinational observational study

University of Cape Town, Cape Town, South Africa and University of Liverpool, UK

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The utility and limitations of clinical trials and cohort studies to determine treatment efficacy during

a disease outbreak

Centre for Integrated Critical Care Research, Department of Medicine and Radiology, University of Melbourne, Melbourne, Australia

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Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort

The ISARIC Clinical Characterisation Group

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COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

The ISARIC Clinical Characterisation Group

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Analysis Plan for ISARIC International COVID-19
Critically Ill Cohort

ISARIC, University of Oxford, UK

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The value of open-source clinical science in pandemic response: lessons from ISARIC

The ISARIC Clinical Characterisation Group 

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Lymphopenia in severe COVID-19 patients: are they a unique immunologically compromised population?

Hospital São Francisco Xavier, Portugal, and University Technology MARA, Malaysia

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Cardiovascular impact in COVID-19 patients: a multicenter cohort analysis

Hospital São Francisco Xavier, and Universidade Algarve Portugal, and University Technology MARA, Malaysia

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COVID-19 among healthcare workers in a worldwide multicentre study: geographical distribution, characteristics and outcomes

National Institute for Communicable Diseases, South Africa and CUB-Hôpital Erasme, Belgium

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Risk to admission of COVID19 patients from the Emergency Department

Universidad del Cauca, Colombia, and Hospital Universitario La Paz, Spain

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COVID-19 among healthcare workers in a worldwide multicentre study: geographical distribution, characteristics and outcomes

National Institute for Communicable Diseases, South Africa and CUB-Hôpital Erasme, Belgium

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Risk to admission of COVID19 patients from the Emergency Department

Universidad del Cauca, Colombia, and Hospital Universitario La Paz, Spain

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Potassium in COVID-19 patients admitted to hospital

Inserm, Nancy Regional and University Hospital Center and INI-CRCT Network, France, and Hospital Civil de Guadalajara, Mexico

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The utility and limitations of clinical trials and cohort studies to determine treatment efficacy during a disease outbreak

University of Melbourne, Australia, All India Institute Of Medical Sciences, India, and Sunnybrook Health Sciences Centre, Canada

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Influence of nutrition status on COVID-related outcome

CUB-Hopital Erasme, Belgium

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Utility of measures of oxygenation for COVID-19 case management and outcome

University of Oxford, UK, Apollo Hospitals Group, India, and Luxembourg Institute of Health, Luxembourg

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Coagulopathy and thrombosis among COVID-19 patients

University of Utah School of Medicine, USA and Fundação Oswaldo Cruz, Brazil

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Neurological manifestation and outcome for patients admitted to hospital with COVID-19

Johns Hopkins University School of Medicine, USA and University of Cape Town, South Africa

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Acute Kidney Injury in COVID-19

University of Queensland, Australia and Universidad Mayor de San Simon, Cochabamba, Bolivia

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Analysis of the ISARIC International COVID-19 Critically Ill Cohort

British Columbia Children’s Hospital, Canada and Universidad De La Sabana, Columbia

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Development of a predictive analytics model for need of extracorporeal support in COVID-19

Washington University in St Louis, USA, INOVA Fairfax Hospital, USA and National Cardiovascular Center Harapan Kita, Indonesia

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Analysis of non-UK cohort in ISARIC COVID-19 data platform

University of Oxford, UK

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International comparison of age-specific presenting symptoms for patients admitted to hospital with coronavirus disease 2019

University of Oxford, UK

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Time variation in the inpatient journey

University of Oxford, UK

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DAC approved proposals

These analyses have been approved by the COVID-19 Data Access Committee (DAC).

Avoiding preventable deaths through the provision of essential treatment in critical illness in the COVID-19 pandemic

London School of Hygiene & Tropical Medicine and Centre for Global Development, UK, Ifakara Health Institute, Tanzania, and Karolinska Institute, Sweden

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Sepsis in COVID-19

Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China

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COVID-Intelligence, a Bayesian Network Clinical Decision Support System for COVID-19

Monash University, Australia

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Clinical presentation and outcome of hospitalised Dutch patients with COVID-19

Franciscus Gasthuis and Vlietland, Rotterdam, The Netherlands

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