COVID-19 Long term protocol

Long term follow-up protocol and study

 

The ISARIC COVID-19 follow up protocol is built on ISARIC/WHO COVID-19 clinical characterisation protocol (CCP). It assesses risk of and risk factors for long-term physical and psychosocial health consequences following COVID-19 diagnosis using a range of validated tools.

 This protocol will follow up patients with confirmed COVID-19 using standardised data collection forms.

The forms can be completed as patient self assessment via post or an online link, or via clinician/research led completion via telephone or in-clinic. It can be used to identify people for further in-clinic follow up and assessment, or in conjunction with sampling and diagnostic studies.

Global COVID-19 Long term follow up study timeline

Click image to zoom

There are three data collection forms/surveys:

  • Tier 1 Initial Freestanding follow up survey – use for any person (hospitalised or not hospitalised) at the first follow up assessment

OR

  • Tier 1 Initial Follow up survey – use for a person with a Core or Rapid CRF completed during an acute hospital admission at the first assessment
  • Tier 1 Ongoing survey – for additional assessment time points

For those already using the Core or Rapid CRFs – the follow up form can be found at the end of the acute, Core and Rapid forms.

The forms are available to sites as open access, to download from our website, and as electronic forms on a secure REDCap database, hosted at University of Oxford, UK. New sites are welcome to:

  • join this open access collaborative study at any time
  • use the forms for independent studies
  • contribute data to collaborative international studies

Sites are responsible for ensuring that they have local ethical approval in place.  

For sites already following up patients using other forms, contact us to discuss options for sharing the data already collected.

To join this collaborative effort, register on the REDCap database or for further information contact: ncov@isaric.org

For scientific questions, or to join the ISARIC Global Follow up working group contact the study co-lead on: louise.sigfrid@ndm.ox.ac.uk

 

Tier 1 follow-up study supporting documents.

Download the study protocol and the survey documents here.

ISARIC COVID-19 follow-up study protocol

Initial follow up survey

Initial freestanding survey

Ongoing follow up survey

Information and consent form

Initial survey telephone script

Follow-up surveys

Paediatric follow-up

ISARIC Global COVID-19 follow up working group

 Louise Sigfrid, John Amuasi, Fernando Bozza, Ibrahim Richard Bangura, Anders Benjamin Kildal, Jan Cato Holter, Luis Felipe Reyes Velasco, Jordi Rello, Daniel Munblit, Antonia Ho, Lance Turtle, Clark Russell,  Anne Margarita Dyrholt-Riise, Carlo Palmieri, Edwin Jesudason, Wei Shen Lim, Muge Cevik, Tom Drake, Katrina Hann, Anna Beltrame, Madiha Hashmi, Sulaiman Lakoh, Jo McPeake, Colin Berry, David Lowe, Natalie Elkheir, Ellen Pauley, Annemarie Docherty, Ewen Harrison, Waasila Jassat, Murray Dryden, Malcom G Semple, Kenneth J Baille, Gail Carson, Janet Scott, Long Covid Support.