ISARIC News

Researchers from Madagascar, UK successfully enrol over 220 cases for landmark plague trial

Researchers from Madagascar, UK successfully enrol over 220 cases for landmark plague trial

IMASOY, a randomised controlled trial to evaluate the efficacy and safety of treatments for bubonic plague, has enrolled over 220 cases of confirmed or probable bubonic plague in Madagascar, marking a critical milestone in plague treatment research. 

Children hospitalised with Omicron did not have a higher risk of experiencing long-term health issues compared to other infections, finds latest study

Children hospitalised with Omicron did not have a higher risk of experiencing long-term health issues compared to other infections, finds latest study

8 February 2024: A new study finds that children hospitalised with initial COVID-19 variant showed more signs of dermatological, fatigue, gastrointestinal, sensory, and sleep issues, as well as behavioural and emotional problems.

Public health vision led by ISARIC partners aims to tackle Nipah virus

Public health vision led by ISARIC partners aims to tackle Nipah virus

15 January 2024: In a new paper published in The Lancet Infectious Diseases, researchers based in Bangladesh, Oxford and Geneva call for a comprehensive public health framework to counter Nipah virus and other neglected infectious diseases with pandemic potential.

ISARIC/RESPIRE Career Development Fellows Complete Global Placements

ISARIC/RESPIRE Career Development Fellows Complete Global Placements

16 November 2023: Three scientists who were awarded a Career Development Fellowship by the International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) and the NIHR Global Health Research Unit on Respiratory Health (RESPIRE) have completed 2-week placements with research teams in Brazil and the Philippines.

The Pandemic Sciences Institute hosted the ‘Key Features of Technology Platforms for R&D to Rapidly Respond to New Outbreaks’ Webinar

The Pandemic Sciences Institute hosted the ‘Key Features of Technology Platforms for R&D to Rapidly Respond to New Outbreaks’ Webinar

The Pandemic Sciences Institute hosted the 'Key Features of Technology Platforms for R&D to Rapidly Respond to New Outbreaks' Webinar.

A multi-country study of monkeypox being launched – first cases enrolled in Geneva

A multi-country study of monkeypox being launched – first cases enrolled in Geneva

Researchers start new investigation into Long COVID core outcome set

A group of researchers started this project with the aims of understanding what are the core outcomes for patients living with Long COVID.

ISARIC COVID-19 clinical database passes the half million patient records mark

ISARIC COVID-19 clinical database passes the half million patient records mark

On its 10th anniversary, University of Oxford’s ISARIC (International Severe Acute Respiratory and Emerging Infection Consortium) demonstrates the crucial role of global preparedness and collaboration for advancing knowledge on infectious disease pandemics.

Children older than 6 and with reported allergic diseases are at greater risk of Long COVID, paediatric study finds

Researchers from ISARIC (International Severe Acute Respiratory and emerging Infection Consortium) paediatric Long Covid working group in the UK, Sechenov University and Z.A. Bashlyaeva Children’s Municipal Clinical Hospital in Russia ran the largest study to date on children hospitalised with COVID 19.

Women under 50 had worse long-term outcomes after hospitalisation with COVID-19

Women under 50 had worse long-term outcomes after hospitalisation with COVID-19

Women under 50 and people who experienced severe disease had worse long-term outcomes following hospitalisation with COVID-19.

Key inflammatory markers identified in COVID-19

Key inflammatory markers identified in COVID-19

ISARIC, supported by the UK Coronavirus Immunology Consortium (UK-CIC), has identified new biomarkers of inflammation that both indicate the severity of COVID-19 and distinguish it from severe influenza.

Long COVID: tackling a multifaceted condition requires a multi- disciplinary approach

Long COVID: tackling a multifaceted condition requires a multi- disciplinary approach

The Lancet Infectious Diseases  published the GloPID-R and ISARIC Long COVID Forum Working Group’ letter, describing the content and discussions of the Long COVID Forum which took place on 9-10 December 2020.

Characterisation of the first 250 000 hospital admissions for COVID-19 in Brazil: a retrospective analysis of nationwide data

Characterisation of the first 250 000 hospital admissions for COVID-19 in Brazil: a retrospective analysis of nationwide data

“These regional differences in mortality reflect differences in access to better health care that already existed before the pandemic”, explains Fernando Bozza, study coordinator and researcher at the National Institute of Infectious Disease.

Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study

Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study

The QCOVID is a new risk prediction tool that uses readily available information about people, such as their age, ethnicity and whether they have certain comorbidities to help identify individuals at highest risk of developing severe illness. 

Genetic mechanisms of critical illness in Covid-19

Genetic mechanisms of critical illness in Covid-19

“Genetic evidence is second only to clinical trials as a way to tell which treatments will be effective in a disease.”

6-month consequences of COVID-19 in patients discharged from hospital: a cohort study

6-month consequences of COVID-19 in patients discharged from hospital: a cohort study

The long-term health consequences of COVID-19 remain largely unclear. The aim of this study was to describe the long-term health consequences of patients with COVID-19 who have been discharged from hospital and investigate the associated risk factors, in particular disease severity.

IDDO and ISARIC partner to support data collection and analysis for COVID-19

IDDO and ISARIC partner to support data collection and analysis for COVID-19

In January 2020, ISARIC launched an international initiative for standardised COVID-19 clinical data collection. Over the past nine months, there has been extensive global participation, resulting in one of the world’s largest collections of comprehensive clinical data for COVID-19.

Global consortium launches new study into long-term effects of COVID-19

Global consortium launches new study into long-term effects of COVID-19

ISARIC, based at Oxford University, in collaboration with Dr Janet Scott, of the MRC-University of Glasgow’s Centre for Virus Research, has launched a longitudinal observational study to measure prevalence and risk factors of long-term health and psychosocial consequences of COVID-19.

New global covid-19 long term study launched

New global covid-19 long term study launched

The international, multi-site study is launched by ISARIC to measure prevalence and risk factors of long-term health and psychosocial consequences of COVID-19. The researchers are inviting hospitals and healthcare sites worldwide to join this new study.

A global study to determine COVID-19 health and psychosocial consequences

A global study to determine COVID-19 health and psychosocial consequences

Even as the COVID-19 pandemic enters into its ninth month, much remains unknown about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and COVID-19 disease. One such area is the possible long-term consequences of SARS-CoV-2 infection and the risk factors for pathological conditions resulting from the disease.

ISARIC collaboration: New national study into the long-term health impacts of COVID-19 launched

ISARIC collaboration: New national study into the long-term health impacts of COVID-19 launched

A major UK research study into the long-term health impacts of COVID-19 on hospitalised patients, involving researchers from the University of Liverpool, has been launched. The PHOSP-COVID study has been awarded £8.4million jointly by UK Research and Innovation (UKRI) and the National Institute for Health Research (NIHR).

Newly Created: GloPID-R’s Clinical Trial Networks Working Group

Newly Created: GloPID-R’s Clinical Trial Networks Working Group

Various clinical trial networks are being funded by GloPID-R members to ensure a rapid clinical research response to epidemics. The Clinical Trial Networks Working Group (CTN WG) provides the opportunity for networks like ISARIC to meet regularly and learn about each other’s work.

Dr John Amuasi (ISARIC member) has been awarded funding!

Dr John Amuasi (ISARIC member) has been awarded funding!

As part of the response to the emergence of COVID-19, the World Health Organization Africa Regional Office (WHO/AFRO) is organising various infection, prevention and control (IPC) and critical care training activities targeted at low- and middle-income countries in Africa.

The Nuffield Department of Medicine is supporting global efforts in tackling nCoV

The Nuffield Department of Medicine is supporting global efforts in tackling nCoV

Professor Peter Horby summarizes ISARIC's recently launched international protocol which will enable investigators to manage all the data and samples they've collected.

ISARIC responding to the Wuhan novel coronavirus outbreak

ISARIC responding to the Wuhan novel coronavirus outbreak

The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) is adapting its existing tools, designed for emerging respiratory pathogens, for the current outbreak of global significance.

New Statement on Data Sharing signed by ISARIC

New Statement on Data Sharing signed by ISARIC

ISARIC has signed a new statement on sharing research findings and data relevant to the Ebola outbreak in the Democratic Republic of Congo. Anyone interested in signing should get in touch with Katherine Littler (K.Littler@wellcome.ac.uk) directly.

NEW ISARIC’s members publication: The hidden burden of influenza

NEW ISARIC’s members publication: The hidden burden of influenza

A review of the extra-pulmonary complications of influenza infection.

Ebola_CP Trial: First plasma donated by survivors in Sierra Leone

Ebola_CP Trial: First plasma donated by survivors in Sierra Leone

First Ebola survivors in Sierra Leone have donated plasma within the Ebola_CP trial led by Calum Semple (ISARIC WG2 Chair) and a team of scientists at the University of Liverpool and the College of Medicine and Allied Health Services, in Sierra Leone.