One of the Oxford Doctors in full PPE, Sierra Leone 2015, Port Loko. Credit: Rebecca Inglis
We have developed a several open access resources to enable global standardised clinical data collection, research and training. Alongside these, we have clinical data reports that are updated regularly thanks to the efforts of the contributors to our ever-growing data base.
We have recently launched a study on Long COVID and welcome interested sites to join this study aiming to identify prevalent symptoms after hospital discharge.
We are currently conducting a randomised controlled trial to compare two treatment regimens for plague. This trial is being conducted in rural health centres across Madagascar and will end enrolling participants at the end of the current plague season by March 2024.
We are aiming to set-up an expanded access protocol for patients diagnosed with mpox. This project is in the early stages of development and further details will be released at a later date.
With the input of a broad range of stakeholders, we have developed a roadmap for a regionally-owned, end-to-end approach towards developing, testing and making available therapies for Lassa fever, adopting a public health-driven portfolio approach to select and deliver the most promising options in an efficient way.
The World Health Organization identifies dengue as one the world’s top ten threats to human health. We are supporting a coordinated global response to develop improved research methods, understand changes in clinical epidemiology, and support clinical trials of new treatments.
Severe Acute Hepatitis
We have consulted with a number of agencies working on severe acute hepatitis of unknown aetiology in children. ISARIC’s global position is to work with the World Health Organization (WHO) on a data collection tool to ensure international standardised data collection, should it be required.
(Short PeRiod IncideNce sTudy of Severe Acute Respiratory Infection)
An effective epidemic response depends on how well prepared we are. This starts before the pandemic begins. The ISARIC SPRINT-SARI study is a global prospective observational study that has been enrolling patients with severe acute respiratory infections since 2015, increasing knowledge of these infections in inter-epidemic times, in preparation for a future pandemic.