ISARIC provides a collaborative platform through which global, patient‐oriented clinical studies can be developed, executed and shared.

 Protocols addressing the most important questions between and during epidemics of severe acute respiratory infections and other rapidly emerging public health threats are undertaken in order to generate new knowledge, maximise the availability of clinical information, and thereby save lives.

International Severe Acute Respiratory and emerging Infection Consortium

LATEST: MONKEYPOX RESPONSE

The ISARIC-WHO Clinical Characterisation Protocol has been activated in the UK and an updated case report form has been shared with ISARIC Partners in other countries for implementation. ISARIC also has an observational cohort study, currently being used in Central African Republic, and now expanding across Europe. Click here for a summary of ISARIC Monkeypox activities.

 

Researchers have launched a new study to improve our understanding of monkeypox disease. The first patients have now been recruited at Hôpitaux Universitaires de Genève (HUG) in Switzerland. Click here to read more.

What we do

Our purpose is to prevent illness and deaths from infectious disease outbreaks.

We are a global federation of clinical research networks, providing a proficient, coordinated, and agile research response to outbreak-prone infectious diseases.

COVID-19 resources:

In December 2019, a novel coronavirus (SARS-CoV-2) emerged to cause a pandemic of a severe coronavirus disease (COVID-19). ISARIC has created tools for investigators to collect and store data in a standardised way and has supported clinical trials of treatments.

Publication library

Visit this section to find ISARIC’s articles, studies and more.

See below our featured research areas: 

COVID-19 CCP

COVID-19
Follow-up study

Lassa fever

Ebola
Data Tools

If you want to use these research tools or if you require further information, please contact the ISARIC team: gsc@isaric.org

Latest news

Children hospitalised with Omicron did not have a higher risk of experiencing long-term health issues compared to other infections, finds latest study

Children hospitalised with Omicron did not have a higher risk of experiencing long-term health issues compared to other infections, finds latest study

8 February 2024: A new study finds that children hospitalised with initial COVID-19 variant showed more signs of dermatological, fatigue, gastrointestinal, sensory, and sleep issues, as well as behavioural and emotional problems.

Public health vision led by ISARIC partners aims to tackle Nipah virus

Public health vision led by ISARIC partners aims to tackle Nipah virus

15 January 2024: In a new paper published in The Lancet Infectious Diseases, researchers based in Bangladesh, Oxford and Geneva call for a comprehensive public health framework to counter Nipah virus and other neglected infectious diseases with pandemic potential.

Draft Framework for Clinical Trials Now Open for Feedback

Draft Framework for Clinical Trials Now Open for Feedback

18 December 2023: The International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) is working with partners to create a framework on endpoint selection for clinical trials for outbreak-prone infectious diseases. This call for a public consultation invites feedback on what the framework does well, what could be improved and the limits of its potential application.

Use of convalescent plasma in patients hospitalised with COVID-19

Use of convalescent plasma in patients hospitalised with COVID-19

Event date - 10/06/2021

Plasma from patients who have recovered from SARS-CoV-2 infection (convalescent plasma) contains antibodies that can bind to and neutralise the virus.

Non-invasive ventilation strategies in COVID-19 – sharing experiences

Non-invasive ventilation strategies in COVID-19 – sharing experiences

Event date - 17/12/2020

This forum aims to review evidence and strategies for Non-invasive ventilation (NIV) in COVID, develop and promote research ideas and evidence-based practice.

Long COVID Forum: 9-10 December 2020

Long COVID Forum: 9-10 December 2020

Event date - 09/12/2020

Currently very little is known about the clinical, biological, psychological and socio-environmental impact of Coronavirus Disease 2019 (COVID-19). While most people have uncomplicated recoveries, some continue to live with prolonged illness and symptoms.

/ˌi.ˈsɑ.rɪk/ ("ee-sa-ric")

From Aramaic איסריא (isaraya), "a bondsman;"

from base word איסרא (isara), "a bond, tie, or binding;"

from Aramaic root אסר (asr), "to bind"