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Bubonic Plague Treatment Proven Highly Effective and Safe in Global First

Bubonic Plague Treatment Proven Highly Effective and Safe in Global First

by Isobel Young | Aug 6, 2025 | News, Partnerships, Publications

Researchers from the UK and Madagascar, in collaboration with Madagascar’s health services and national plague programme, have conducted the world’s first rigorous clinical trial of treatments for bubonic plague. The IMASOY trial provides the first robust evidence of...

An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus an aminoglycoside + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial-an update to the published protoco

by Wajeeha Malik | Jul 5, 2024

An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus streptomycin + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial

by Wajeeha Malik | May 14, 2024

Researchers successfully enrol over 220 cases for landmark plague trial

Researchers successfully enrol over 220 cases for landmark plague trial

by Wajeeha Malik | May 8, 2024 | News

The first randomised controlled trial powered to evaluate the efficacy and safety of treatments for bubonic plague has enrolled over 220 cases of confirmed or probable bubonic plague in Madagascar, marking a critical milestone in plague treatment research.  Plague has...

The impact of COVID-19 on clinical research for Neglected Tropical Diseases (NTDs): a case study of bubonic plague

by Eamonn | Apr 23, 2024

Among the many collaterals of the COVID-19 pandemic is the disruption of health services and vital clinical research. COVID-19 has magnified the challenges faced in research and threatens to slow research for urgently needed therapeutics for Neglected Tropical...
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