A prospective public health surveillance study in epidemiology and outcomes of patients hospitalised with Dengue in South Asia
A standardised observational framework to characterise dengue clinical epidemiology and address critical knowledge gaps to improve patient outcomes.
Objectives:
- To describe the clinical presentation, demographics, including socio-economic determinants, illness severity, biochemical and haematological abnormalities, treatments received (fluids, vasopressors, organ support strategies, antiviral and anti-inflammatory medications) and outcomes for all dengue patients admitted to participating hospitals and ICUs over a 6-month period.
- To evaluate treatment-related predictors of mortality for the cohort of severe dengue patients admitted to ICUs using modern causal inference approaches
Research questions:
- For patients hospitalized with Dengue, what are the patterns of clinical presentation, illness severity, treatments received, and outcomes?
- What are the patient and treatment-related predictors of hospital mortality for the cohort of severe dengue patients admitted to ICUs?
Resources:
If you are interested in using or developing this protocol for global use, please contact data@isaric.org