Non-invasive ventilation strategies in COVID-19 – sharing experiences

ISARIC partners have been at the forefront of clinical trials of COVID-19 treatments since the start of the pandemic. Recognising how hard it is to keep up with the extraordinary pace of COVID science, ISARIC will run a series of ‘Evidence Fora’ on COVID-19 treatment.  

These fora will take stock of the current evidence, inform, stimulate debate, and generate new ideas. ISARIC partners and invited experts from across the world will present the ’state-of-the-art’ on:

• Corticosteroids
• Remdesivir
• COVID-19 pathophysiology and treatment options
• Anti-coagulation
• Respiratory support

Our second evidence forum focused on non-invasive ventilation (NIV).

Many patients hospitalised with COVID-19 require respiratory support. However, not all need invasive mechanical ventilation. A range of other options for respiratory support are available, including standard oxygen therapy via a face mask, high-flow nasal oxygen, continuous positive airway pressure (CPAP), and bi-level positive airway pressure (BiPAP).

Published cohort studies show that a range of ventilatory strategies are used in COVID-19-but there is no consensus on which is best. Which type of respiratory support, in which patients, and at what stage of the disease is most effective in reducing the risk of progression to Invasive mechanical ventilation and/or death?

Speakers:

Peter Horby
Executive Director, ISARIC 

Daniel Munblit
Professor, Department of Paediatrics & Paediatric Infectious Diseases, Sechenov University

Ben Messer
Consultant Critical Care/Home Ventilation, Royal Victoria Infirmary

Nikita Nekliudov
Final year Medical Student, Department of Paediatrics & Paediatric Infectious Diseases, Sechenov University

Andrey Yaroshetskiy
Head, Anesthesiology & Critical Care Department, Research Institute for Clinical Surgery, Sechenov University

Sergey Avdeev
Professor of Respiratory Medicine, Pulmonology Research Institute, Sechenov University

Bronwen Connolly
Senior Lecturer, Wellcome-Wolfson Institute for Experimental Medicine, Queen’s University Belfast

Armand Mekontso Dessap
Head, Critical Care Unit Medicine at Henri Mondor Hospital, University of Paris East Creteil, France, & Director of the CARMAS Research Group

Tim Baker
Associate Professor, Department of Clinical Research at the London School of Hygiene and Tropical Medicine

Annemarie Docherty
Clinical Lecturer Anaesthesia and ICM at University of Edinburgh

Objectives of this forum:

• To share experiences of different ventilation strategies in COVID-19.
• To identify key outstanding questions on optimal ventilation strategies in COVID-19.

 

If you require this event’s transcription, please email us at gsc@isaric.org