Dengue Clinical Characterisation Protocol

A standardised observational framework to characterise H5Nx clinical epidemiology and address critical knowledge gaps to improve patient outcomes.

A comprehensive understanding of dengue clinical epidemiology is essential to tailor public health responses and design clinical trials to improve supportive care and therapeutics.

The ISARIC-WHO Clinical Characterisation Protocol (CCP) is a standardised approach to rapid, coordinated clinical investigation of any acute infections of public health interest including dengue.

ISARIC has partnered with global experts to develop a dengue CRF and adapt data collection and analytics tools for dengue, enabling research to : 

  • Characterise the clinical presentation of cases, including the natural history, progression, and variability of symptoms.
  • Identify risk factors and outcomes associated with the disease
  • Inform better case management strategies, contribute to the design of clinical trials, and guide public health interventions.

To know more about how to implement CCP Dengue

Regional implementation

Some sites have developed a local or regional adaptation of the protocol for their context.

    • A prospective public health surveillance study in epidemiology and outcomes of patients hospitalised with Dengue in South Asia. Learn more.
    • A Severe Dengue study in Sao Paul, Brazil
    • A Severe Dengue study in Bangladesh

In collaboration with:

For more information and to join the efforts against dengue, contact data@isaric.org

Related people

Leadership