ISARIC has been committed to provide a wide breadth of COVID-19 clinical research resources since the beginning of the outbreak. These resources are fully adaptable and completely free to use

The tools below aim to cover a range of tiers, suitable for different needs. Whether you are aiming to just collect standardised data, contribute with your data to ISARIC’s ever growing clinical database or start your own study on COVID-19, ISARIC’s COVID-19 presents fully adaptable data collection solutions for different needs.

Professor Bin Cao with a COVID-19 patient (Photo credit: Professor Bin Cao, China-Japan Friendship Hospital, China)


For the collection of standardised clinical data to improve patient care and inform the public health response.

The ISARIC-WHO Case Report Forms (CRFs) should be used to collect data on individuals presenting with suspected or confirmed COVID-19.

Optional CRF Modules

These modules have been developed in collaboration with WHO and international experts to be used in addition to the Core or RAPID COVID-19 CRFs when applicable, depending on resources and research need.

We currently have two modules available: COVID-19 Rapid Critical Care and COVID-19 CRF Module for Pregnant Women

Multisystem inflammatory syndrome (MIS-C) in children and adolescents

This CRF has been developed in collaboration with WHO’s working group.

This Case Report Form (CRF) has been developed to use as a standalone CRF for children and adolescents presenting with syndrome of suspected Multisystem Inflammatory Syndrome (MIS-C).

COVID-19 Data Management & Hosting

The ISARIC Clinical Data Platform is a secure electronic data capture system and repository that standardises and secures global data on COVID-19.

Ownership and control of all data entered on this system are retained by those who enter the data.

COVID-19 Evidence & Data Reports

ISARIC Partners are invited to lead and participate in collaborative analyses of the ISARIC Global Data Platform.

Staff from sites and networks contributing to the ISARIC database, defined as ‘ISARIC Partners’, can request to initiate an analysis.

Clinical Characterisation Protocol (CCP)

ISARIC/WHO protocol for standardised clinical data collection (+/- sampling)

The CCP It is a standardised protocol that enables data and biological samples to be collected rapidly in a globally-harmonised manner. It may be used  for the rapid, coordinated clinical investigation of confirmed cases of COVID-19. It is fully adaptable and ISARIC encourages its global use. Data collection forms:
Acute phase (Core, Rapid, optional modules) and Tier 1 follow up survey

COVID-19 Long term protocol & survey

Standardised clinical data collection

Study protocol and a patient survey for serial follow up of patients with confirmed COVID-19, to standardise data collection to facilitate timely, robust analysis to assess frequency and risk factors for long term health and psychosocial consequences of COVID-19.

COVID-19 CCP Global Toolkit

ISARIC has developed developed a range of free downloadable materials to provide guidance on the Global Clinical Characterisation protocol

Visit the toolkit for an overview of the main steps for implementation of the CCP. There are also two case studies available to help guide the implementation process.

COVID-19 Rapid Evidence Reviews Group (CORRE)

A collaborative effort to provide high quality rapid evidence synthesis for use in COVID-19 research.

Reports produced by the COVID-19 Rapid Evidence Reviews Group seek to provide an answer to a list of relevant research questions.

The final purpose is to accelerate our collective understanding of COVID-19 to help improve patient care and inform public health policy.

Associated clinical studies in COVID-19

Clinical data collection with the aims of building a research or study

ISARIC has many member networks, who are involved in patient-based research, to generate an evidence-based response to COVID 19, and has also provided support to several clinical trials, some of which are mentioned here.

Publication library

Visit this section to find ISARIC’s articles, studies and more.

Latest news

A global study to determine COVID-19 health and psychosocial consequences

A global study to determine COVID-19 health and psychosocial consequences

Even as the COVID-19 pandemic enters into its ninth month, much remains unknown about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and COVID-19 disease. One such area is the possible long-term consequences of SARS-CoV-2 infection and the risk factors for pathological conditions resulting from the disease.

ISARIC collaboration: New national study into the long-term health impacts of COVID-19 launched

ISARIC collaboration: New national study into the long-term health impacts of COVID-19 launched

A major UK research study into the long-term health impacts of COVID-19 on hospitalised patients, involving researchers from the University of Liverpool, has been launched. The PHOSP-COVID study has been awarded £8.4million jointly by UK Research and Innovation (UKRI) and the National Institute for Health Research (NIHR).

Newly Created: GloPID-R’s Clinical Trial Networks Working Group

Newly Created: GloPID-R’s Clinical Trial Networks Working Group

Various clinical trial networks are being funded by GloPID-R members to ensure a rapid clinical research response to epidemics. The Clinical Trial Networks Working Group (CTN WG) provides the opportunity for networks like ISARIC to meet regularly and learn about each other’s work.